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Synephrine by BioTech USA is a capsule supplement that provides 10 mg of synephrine from bitter orange (critrus aurantium) extract per 1 capsule dose.
Synephrine is a central nervous system stimulant chemically very similar to ephedrine and pseudoephedrine but with less harmful effects.
The extract of this fruit has been shown to be able to enhance fat loss, reduce appetite, improve athletic performance and at the same time help maintain muscle tissue even in conditions of caloric deficit.
Synephrine is a central nervous system stimulant chemically very similar to ephedrine and pseudoephedrine but with less harmful effects
Main benefits of Synephrine by BioTech USA:
- Provides 10 mg of synephrine per one capsule dose.
- Helps you increase endurance, duration and intensity of training.
- Improves athletic performance and reduces the feeling of perceived exertion.
- Increases metabolic expenditure at rest.
- Stimulates lipolysis and reduces appetite.
- Does not increase blood pressure or heart rate.
- Presents antidepressant effects.
- 60 servings per container.
P-synephrine (natural form of synephrine present in Citrus aurantium) binds to β-3 adrenergic receptors found in white fat tissue, brown fat tissue and muscle tissue. Activation of these receptors stimulates lipolysis, promotes lipid metabolism and increases metabolic expenditure.
The activation of β-3 adrenergic receptors may also reduce food intake and weight gain, as well as being able to improve insulin sensitivity, glycaemic control and improve plasma lipid parameters.
These same receptors are also found in cardiac tissue but unlike other adrenergic receptors, their activation reduces cardiac stimulation. This means that consumption of p-synephrine (natural synephrine present in Citrus aurantium) does not increase blood pressure or heart rate.
The increase in cardiovascular parameters are due to activation of α-adrenergic receptors (vasoconstriction), β-1 (increased heart rate) and β-2 (bronchodilation) whereas p-synephrine would act on β-3 receptors.
In recent years it has been observed that the activation of the β-3 receptors can regulate the activation of the other receptors modulating and reducing their activation when they are stimulated in excess. Presenting even, protective effects on the cardiovascular system.
On many occasions studies do not specify what type of synephrine has been used or do not differentiate between the two types of synephrine, so it is common to observe contradictions, especially regarding the effects on cardiac tissue.
The structure of synephrine is very similar to ephedrine however, its action is different. Ephedrine does not contain the hydroxyl group that p-synephrine contains. This small detail together with the presence of a methyl group, changes the affinity for adrenergic receptors and reduces the liposolubility of p-synephrine and as a result can hardly access to the central nervous system.
In conclusion, these small modifications in its structure modify its effects on the nervous and cardiovascular system, eliminating the side effects of ephedrine.
Citrus aurantium is used today by many athletes in order to increase endurance and prolong the duration and intensity of physical activity.
The consumption of bitter orange extract has been associated with improved athletic performance and reduced feelings of perceived exertion.
The administration of synephrine from Citrus aurantium (alone or in combination with other ingredients) increases resting metabolic expenditure, stimulates lipolysis and reduces appetite, all without increasing blood pressure or heart rate.
The consumption of p-synephrine in combination with bioflavonoids also present in Citrus aurantium (naringin and hesperidin) enhances the effects on thermogenesis.
Bitter orange extracts containing a high content of synephrine have antidepressant effects.
Bitter orange extracts containing a high content of synephrine have antidepressant effects.
Bitter orange extracts containing a high content of synephrine have antidepressant effects
Caking agent (calcium phosphates), bitter orange extract 19.6% , capsule shell , anti-caking agents (magnesium salts of fatty acids, silicon dioxide).
Manufactured in a factory that produces foods containing milk, eggs, gluten, soya, crustaceans, sulphur dioxide and nuts.
As a dietary supplement for healthy adults, take 1 dose of 1 capsule before meals with a large glass of water.
Do not exceed the expressly recommended daily dose.
Do not exceed the expressly recommended daily dose
Pack of 60 capsules.
Pack of 60 capsules
