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It promotes the energetic nutrition of the osteoarticular system in the body, including cartilage, subchondral bone, and synovial tissue. It activates compensatory mechanisms for the biological effects of free radicals at the osteoarticular level, leading to the restoration of membrane quality for proper intercellular information transfer. It also regulates the energy of immune events that generate joint inflammatory response. It balances the energy of the endocrine axis related to osteoligamentary and articular metabolism. Directions for use: Take 1-2 capsules a day, before breakfast and lunch. Ingredients: Per capsule: Shark cartilage* (8-12% glucosamine sulfate, 14-20% chondroitin sulfate), 75 mg; hydrolyzed fish collagen* (PeptanTM F 5000 HD), 55 mg; OptiMSM® (99.8% methylsulfonylmethane), 50 mg; chondroitin sulfate (shark, 90%), 45 mg; sodium hyaluronate, 3 mg. Quercetin (Sophora japonica L., flower bud, >95%), 32 mg; resveratrol (Polygonum cuspidatum et Zucc, root), 10 mg; reduced L-glutathione (GSH), 2 mg. Dry rosehip extract (Rosa canina, fruit, >0.2% L-ascorbic acid), 27 mg; dry maca extract (Lepidium meyenii, root, ratio 4:1), 22 mg; dry devil's claw extract (Harpagophytum procumbens D.C., root, >2% harpagosides), 12 mg; dry hawkweed extract (Hieracium pilosella L., flower, >0.3% umbelliferone), 5 mg. L-proline, 38 mg; L-tyrosine, 32 mg; L-arginine, 30 mg. Calcium gluconate (8.94% calcium), 12 mg; magnesium gluconate (5.86% magnesium), 6 mg; potassium gluconate (16.69% potassium), 3 mg; tricalcium phosphate (38.76% calcium, 19.97% phosphorus), 3 mg; silicon dioxide, 0.4 mg; vitamin B2 (riboflavin), 0.1 mg; vitamin B6 (pyridoxine hydrochloride), 0.1 mg; vitamin B1 (thiamine hydrochloride), 0.08 mg.